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Fragment-based development of protein-protein interaction inhibitors
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News
Research
Structural Biology of TGF-β signalling
Fragment-based development of protein-protein interaction inhibitors
Publications
People
Social
Group retreats
Resources
Methods
Videos
Proteins
Vacancies
Contact
Paul Brear
Postdoctoral fellow since 2012.
Recent Posts
Microfluidics-enabled fluorescence-activated cell sorting of single pathogen-specific antibody secreting cells for the rapid discovery of monoclonal antibodies
A versatile Halo- and SNAP-tagged BMP/TGFβ receptor library for quantification of cell surface ligand binding
Serendipitous Identification of a Covalent Activator of Liver Pyruvate Kinase
Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2α
A fragment-based approach leading to the discovery of inhibitors of CK2α with a novel mechanism of action
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